Polyphagia

Polyphagia
ICD-10 R63.2
ICD-9 783.6

Polyphagia is weight loss despite increased appetite (initially)[1]. It derives from the Greek words πολύς (polys) which means "very much", and φαγῶ (phago), verb for "I eat".[2]

Contents

In medicine

In medicine, polyphagia (sometimes known as hyperphagia) is a medical sign meaning excessive hunger and abnormally large intake of solids by mouth. Disorders such as diabetes, Kleine-Levin Syndrome (a malfunction in the hypothalamus), the genetic disorders Prader-Willi Syndrome and Bardet Biedl Syndrome can cause hyperphagia (compulsive hunger).[3]

Diabetic ketoacidosis

Polyphagia usually occurs early in the course of diabetic ketoacidosis.[4] However, once insulin deficiency becomes more severe and ketoacidosis develops, appetite is suppressed.[5]

See also

References

  1. ^ Berthoud HR, Lenard NR, Shin AC (2011). "Food reward, hyperphagia, and obesity.". Am J Physiol Regul Integr Comp Physiol 300 (6): R1266-77. doi:10.1152/ajpregu.00028.2011. PMC PMC3119156. PMID 21411768. http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21411768. 
  2. ^ http://yourtotalhealth.ivillage.com/polyphagia.html,
  3. ^ OMIM::Prader-WilliOMIM::Bardet-Biedl
  4. ^ Elliott RE, Jane JA, Wisoff JH (2011). "Surgical management of craniopharyngiomas in children: meta-analysis and comparison of transcranial and transsphenoidal approaches.". Neurosurgery 69 (3): 630-43; discussion 643. doi:10.1227/NEU.0b013e31821a872d. PMID 21499159. 
  5. ^ Masuzaki H, Tanaka T, Ebihara K, Hosoda K, Nakao K (2009). "Hypothalamic melanocortin signaling and leptin resistance--perspective of therapeutic application for obesity-diabetes syndrome.". Peptides 30 (7): 1383-6. doi:10.1016/j.peptides.2009.04.008. PMID 19394382. http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19394382. 

External links